BDBM50518763 CHEMBL4544877

SMILES Cc1nc(-c2ccnc(C)c2)n2c3ncsc3nc(C)c12

InChI Key InChIKey=LXBIRDIHQJGZAB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50518763   

LigandPNGBDBM50518763(CHEMBL4544877)
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Abbvie Deutschland

Curated by ChEMBL
LigandPNGBDBM50518763(CHEMBL4544877)
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Abbvie Deutschland

Curated by ChEMBL
LigandPNGBDBM50518763(CHEMBL4544877)
Affinity DataIC50: 7.85E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed