BDBM50518771 CHEMBL4472614

SMILES COc1cc(OC)c2nnc3n(C)nc(-c4sc(C)nc4C)c3c2c1

InChI Key InChIKey=ZZKGUYYWXGOKCA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50518771   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Abbvie Deutschland

Curated by ChEMBL

LigandBDBM50518771(CHEMBL4472614)Copy SMILESCopy InChI

Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Abbvie Deutschland

Curated by ChEMBL

LigandBDBM50518771(CHEMBL4472614)Copy SMILESCopy InChI

Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/23/2021
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL