BDBM50520277 CHEMBL4586717
SMILES CNC(=O)c1cncc(c1)-c1ccc(C(N)=O)c(OC(C)C)c1
InChI Key InChIKey=UEASTXHAYQBYDW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50520277
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal GST-tagged MNK1 (unknown origin) (37 to 341 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1/2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MNK1/MNK2 in human HeLa cells overexpressing eIF4E assessed as reduction in eIF4E phosphorylation at Ser209 residue after 2 hrs by Alph...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
A*Star
Curated by ChEMBL
A*Star
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of N-terminal GST-tagged MNK2 (unknown origin) (72 to 385 residues) expressed in Escherichia coli BL21 (DE3) cells using 5-FAM-TATKSGSTTKN...More data for this Ligand-Target Pair