BDBM50524649 CHEMBL4562303

SMILES [H][C@]12OC(C)(C)O[C@@]1([H])[C@@]1([H])COCc3cn(C[C@@]4([H])O[C@]([H])(CCN(CCc5ccc6ccccc6c5)CC[C@@]([H])(O1)[C@@H]2OCCC(C)C)[C@H](OCCC(C)C)[C@@]1([H])OC(C)(C)O[C@@]41[H])nn3

InChI Key InChIKey=KBUZNRXQGIRPQQ-UHFFFAOYSA-N

Data  5 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50524649   

Target5-hydroxytryptamine receptor 1A(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: 680nMAssay Description:Displacement of [3H]OH-DPAT from human recombinant 5-HT1A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  1.60E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSubstance-K receptor(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: 3.00E+3nMAssay Description:Displacement of [125I]NKA from human recombinant NK2 receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  4.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi:  8.20E+3nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: 8.70E+3nMAssay Description:Displacement of [3H] ketanserin from human recombinant 5-HT2A receptor measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at human recombinant 5-HT2B receptor in CHOK1 cells measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
National University of Ireland Galway

Curated by ChEMBL
LigandPNGBDBM50524649(CHEMBL4562303)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H] imipramine from human recombinant 5-HT transporter measured after 60 mins by scintillation counter methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed