BDBM50533339 CHEMBL1907858

SMILES [H][C@@]1(Cc2cccc3cccc1c23)N1CCC2(CC1)N(CNC2=O)c1ccccc1

InChI Key InChIKey=BBOAHBVXCYBKLC-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50533339   

TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533339(CHEMBL1907858)
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]-orphanin FQ from human nociceptin opioid receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533339(CHEMBL1907858)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]-naloxone from human mu opioid receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Astraea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50533339(CHEMBL1907858)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human nociceptin opioid receptor expressed in HEK293 cell membranes by GTPgamma(35)S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMed