BDBM50537140 CHEMBL4584630

SMILES Nc1ncnc2n(nc(-c3cn(Cc4nc5ccc(Cl)cn5c4Br)nn3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=GQYYHEIAOSIQRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50537140   

TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537140(CHEMBL4584630)
Affinity DataIC50: 85nMAssay Description:Inhibition of wild type EGFR (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50537140(CHEMBL4584630)
Affinity DataIC50: 104nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed