BDBM50539165 CHEMBL4640817

SMILES COC(=O)[C@@H](N)Cc1cn(-c2nc(Cl)nc(Nc3ccc(cc3)N3CCOCC3=O)n2)c2ccccc12

InChI Key InChIKey=AOAMFXGEGMMVGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50539165   

TargetProstaglandin G/H synthase 2(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50539165(CHEMBL4640817)
Affinity DataIC50: 30nMAssay Description:Inhibition of human COX2 using arachidonic acid as substrate incubated for 10 mins followed by substrate addition and measured after 2 mins by EIA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50539165(CHEMBL4640817)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 10 mins followed by substrate addition and measured after 2 mins by EIA as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed