BDBM50539745 CHEMBL4642347
SMILES CC(C)c1ccc2[nH]ncc2c1N1CCc2c(C1)nc(OC[C@@H]1CCCN1C)nc2N1CCN(CC1)C(=O)C=C
InChI Key InChIKey=PQYZPEBTMDDKNX-NRFANRHFSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50539745
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair