BDBM50539759 CHEMBL4646899
SMILES CCc1cccc2cccc(N3CCc4c(C3)nc(OC[C@@H]3CCCN3C)nc4N3CCN([C@@H](CC#N)C3)C(=O)C=C)c12
InChI Key InChIKey=QHSWWHCSXWHQQP-SVBPBHIXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50539759
Affinity DataIC50: 6nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair