BDBM50539766 CHEMBL4645376
SMILES COC\C=C\C(=O)N1CCN(C[C@@H]1CC#N)c1nc(OC[C@@H]2CCCN2C)nc2CN(CCc12)c1cccc2cccc(Cl)c12
InChI Key InChIKey=MVFNWTXBVIDVFN-VHNSWPBLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50539766
Affinity DataIC50: 9nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair