BDBM50540758 CHEMBL4642139

SMILES O=c1[nH]c(SCCN2CCN(CCCOc3ccc(cc3)-c3ccccc3)CC2)nc2ccccc12

InChI Key InChIKey=CXPJWDXJJXREGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50540758   

TargetPoly [ADP-ribose] polymerase 2(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50540758(CHEMBL4642139)
Affinity DataIC50: 340nMAssay Description:Inhibition of full length human N-terminal His-tagged PARP2 expressed in baculovirus infected Sf9 cells using histone H3.3 as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50540758(CHEMBL4642139)
Affinity DataIC50: 588nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS2 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50540758(CHEMBL4642139)
Affinity DataIC50: 673nMAssay Description:Inhibition of full length human N-terminal GST-tagged TNKS1 ADP-ART catalytic domain (1001 to 1327 residues) using histone H2A as substrate incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Naples

Curated by ChEMBL
LigandPNGBDBM50540758(CHEMBL4642139)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of full length human C-terminal His-tagged PARP1 expressed in baculovirus infected Sf9 cells using chicken core histone as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed