BDBM50547335 CHEMBL3741275
SMILES CN(CCN(C)C(=O)c1coc2ccccc2c1=O)C(=O)c1cn(c2ccccc12)S(=O)(=O)c1cccc(c1)[N+]([O-])=O
InChI Key InChIKey=CASABOSNGORYTE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50547335
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataKd: 4.60E+3nMAssay Description:Binding affinity to GST-fused human RANKL extracellular domain (Lys159 to Asp317 residues) expressed in Escherichia coli BL21(DE3) pLysS by fluoresce...More data for this Ligand-Target Pair
TargetTumor necrosis factor ligand superfamily member 11(Homo sapiens)
Agricultural University Of Athens
Curated by ChEMBL
Agricultural University Of Athens
Curated by ChEMBL
Affinity DataIC50: 5.07E+3nMAssay Description:Inhibition of human RANKL-induced osteoclastogenesis in RANKL cultured mouse bone marrow cells assessed as reduction in RANKL/M-CSF-induced TRAP acti...More data for this Ligand-Target Pair