BDBM50547418 CHEMBL4740085

SMILES COC(=O)N(C)c1c(N)nc(nc1N)-n1nc(Cc2cc(F)cc(F)c2F)c2ccccc12

InChI Key InChIKey=XGTWWTSGIOGZTH-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547418   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50547418(CHEMBL4740085)
Affinity DataEC50:  110nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50547418(CHEMBL4740085)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed