BDBM50547429 CHEMBL4755974

SMILES CC1(C)C(=O)Nc2nc(nc(N)c12)-n1nc(Cc2c(F)ccc(F)c2F)c2ccccc12

InChI Key InChIKey=NXIBFDKAAHJUKJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50547429   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50547429(CHEMBL4755974)
Affinity DataEC50:  2.00E+3nMAssay Description:Activation of human sGC subunit alpha1/beta1 expressed in CHO cells assessed as cGMP production by CASA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50547429(CHEMBL4755974)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed