BDBM50548182 CHEMBL4759780

SMILES ONC(=O)c1ccc(Cn2c(=O)c(F)cn(C3CCCO3)c2=O)cc1

InChI Key InChIKey=JRJCDFNDSLVBOP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50548182   

TargetHistone deacetylase 2(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50548182(CHEMBL4759780)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human HDAC2 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50548182(CHEMBL4759780)
Affinity DataIC50:  1.71E+3nMAssay Description:Inhibition of human HDAC1 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM50548182(CHEMBL4759780)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC6 using p53 fluorogenic peptide (379 to 382 residues) RHKKAc as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed