BDBM50550262 CHEMBL4762396

SMILES C[C@@H]1CN(CCN1c1nccc(n1)C(=O)NC1C2CC3CC1CC(O)(C3)C2)c1ccc(cc1F)C(C)(C)O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50550262   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Sk Chemicals

Curated by ChEMBL
LigandPNGBDBM50550262(CHEMBL4762396)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells using cortisone in presence of NADPH regenerating-system incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed