BDBM50552211 CHEMBL4751074

SMILES [H][C@@]12CC[C@H](N1S(=O)(=O)N[C@@H]2c1cc(cc(c1)C(F)(F)F)C(F)(F)F)c1cc(ccc1-c1cc(ccc1OC)[C@H]1CC[C@@H](CC1)C(O)=O)C(F)(F)F

InChI Key InChIKey=UYRKDRGFMYVLBT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50552211   

TargetCholesteryl ester transfer protein(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50552211(CHEMBL4751074)
Affinity DataIC50: 394nMAssay Description:Inhibition of recombinant CETP (unknown origin) assessed as inhibition of transfer of [3H] cholesteryl oleate or [3H] triolein between exogenous LDL ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50552211(CHEMBL4751074)
Affinity DataIC50: 2.68E+3nMAssay Description:Inhibition of CETP in 95% human serum assessed as inhibition of transfer of [3H] cholesteryl oleate or [3H] triolein between LDL and HDLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed