BDBM50553869 CHEMBL4764965

SMILES C=CC(=O)Nc1cc(cc(c1)-c1n[nH]c2ccccc12)C(=O)NCC#C

InChI Key InChIKey=QLVGPPRZJNJOLD-UHFFFAOYSA-N

Data  2 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50553869   

TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of MAP2K7 (unknown origin) using JNK peptide KFMMTPYVVTR incubated for 30 mins measured by multimode reader based ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataEC50: <100nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) in human U2OS assessed as reduction in c-Jun phosphorylation level incub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDual specificity mitogen-activated protein kinase kinase 7(Homo sapiens (Human))
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM50553869(CHEMBL4764965)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of N-terminal 6XHis-tagged recombinant MKK7 (117 to 423 residues) (unknown origin) expressed in Escherichia coli BL21-DE3 preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB