BDBM50562452 CHEMBL4776197
SMILES Nc1cc(cc2nc(c(Nc3ccc(cc3)C(=O)N3CCC(CC3)C(O)=O)nc12)-c1ccccc1)C(F)(F)F
InChI Key InChIKey=WOYFMXSNNXPPRD-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50562452
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Leishmania major)
Comsats University Islamabad
Curated by ChEMBL
Comsats University Islamabad
Curated by ChEMBL
Affinity DataKi: 1.70E+4nMAssay Description:Inhibition of Leishmania major DHFR assessed by NADPH oxidation measured by spectrophotometric methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.40E+4nMAssay Description:Inhibition of human DHFR assessed by NADPH oxidation measured by spectrophotometric methodMore data for this Ligand-Target Pair