BDBM50562491 CHEMBL4744710

SMILES CCN(CC)Cc1ccc(Cn2c3ccccc3c(-c3cccnc3)c(OCc3ccc(cc3)C(=O)NO)c2=O)cc1

InChI Key InChIKey=JZWQUCQSANRYGU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50562491   

TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  319nMAssay Description:Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Z-(Ac)Lys-AMC as substrate m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 cells using Z-(Ac)Lys-AMC as substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  12nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  319nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50562491(CHEMBL4744710)
Affinity DataIC50:  490nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor-de-Lys as substrate measured after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed