BDBM50563494 CHEMBL4781622

SMILES Fc1ccc(NC(=O)c2n[nH]cc2NC(=O)c2c(F)ccc(c2F)-c2cccc(c2)C(=O)NCCCN2CCOCC2)cc1

InChI Key InChIKey=YIEUCLWKZPZZLL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563494   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50563494(CHEMBL4781622)
Affinity DataIC50:  73nMAssay Description:Inhibition of CDK2/cyclin A2 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Shanghaitech University

Curated by ChEMBL
LigandPNGBDBM50563494(CHEMBL4781622)
Affinity DataIC50:  723nMAssay Description:Inhibition of CDK1/cyclin B1 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed