BDBM50565591 CHEMBL4783308
SMILES Cn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12
InChI Key InChIKey=GZWDPKFZWIXEQI-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50565591
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 1.20nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair