BDBM50565595 CHEMBL4785006
SMILES CCCCn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12
InChI Key InChIKey=BCXKEPWQDBIUCL-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50565595
TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison
Curated by ChEMBL
University Of Wisconsin-Madison
Curated by ChEMBL
Affinity DataEC50: 0.280nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair