BDBM50565595 CHEMBL4785006

SMILES CCCCn1cc(C(=O)c2nc3ccc(F)cc3n2C)c2cccc(F)c12

InChI Key InChIKey=BCXKEPWQDBIUCL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50565595   

TargetProprotein convertase subtilisin/kexin type 9(Homo sapiens (Human))
University Of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50565595(CHEMBL4785006)
Affinity DataEC50:  0.280nMAssay Description:Modulation of PCSK9 in human HepG2 cells assessed as reduction in PCSK9 expression incubated for 24 hrs prior to compound washout followed by compoun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed