BDBM50572886 CHEMBL4866741

SMILES OC(=O)c1ccc(cc1C1CCCC1)-c1coc2ncc(cc12)-c1ccccc1

InChI Key InChIKey=GZZXEPJJXLJJEJ-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50572886   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572886(CHEMBL4866741)
Affinity DataIC50:  65nMAssay Description:Inhibition of human CAMKK2 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCalcium/calmodulin-dependent protein kinase kinase 1(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572886(CHEMBL4866741)
Affinity DataIC50:  961nMAssay Description:Inhibition of human CAMKK1 using CAMKKtide as substrate assessed as residual activity by [gamma-33P]-ATP assay relative to controlMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50572886(CHEMBL4866741)
Affinity DataIC50:  700nMAssay Description:Inhibition of NanoLuc-fused CAMKK2 (unknown origin) expressed in HEK293 cells after 24 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB