BDBM50573589 CHEMBL4864883

SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCCCCc3ccccc3)nc(Cl)nc12

InChI Key InChIKey=AIJPTCVDEDYCCU-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573589   

TargetAdenosine receptor A3(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50573589(CHEMBL4864883)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in HeLa cell membrane incubated for 180 mins by microplate beta scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50573589(CHEMBL4864883)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human adenosine A3 receptor transfected in CHO cells assessed as cAMP level measured after 35 mins by cAMP enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50573589(CHEMBL4864883)
Affinity DataKi:  3.34E+3nMAssay Description:Displacement [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membrane incubated for 60 mins by microplate beta scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Institute of Medical Biology Pas

Curated by ChEMBL
LigandPNGBDBM50573589(CHEMBL4864883)
Affinity DataIC50: 2.20E+4nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in HeLa cells by beta scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed