BDBM50574091 CHEMBL4847680

SMILES Cn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(s1)-c1cccc(Cl)c1

InChI Key InChIKey=JGDCBWHESDAKNG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50574091   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 53nMAssay Description:Inhibition of FLT3 (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Aurora A (unknown origin) using 5' FAM-LRRASLG-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 6.83E+3nMAssay Description:Inhibition of RET (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 8.56E+3nMAssay Description:Inhibition of CSF-1R (unknown origin) using 5' FAM-KKKKEEIYFFF-CONH2 peptide as a substrate in the presence of ATP incubated for 60 mins by microflui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of NIK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Nek2(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NEK2 (unknown origin) using 5' FAM-KKLNRTLSVA-COOH peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50574091(CHEMBL4847680)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) using 5' FAM-EPLYWSFPA peptide as a substrate in the presence of ATP incubated for 60 mins by microfluidics assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed