BDBM50574216 CHEMBL4876214::US20240000767, Example 108

SMILES Fc1cnc(CNC(=O)c2cnc(s2)N2CCC(CC2)N2CCCC(C2)OCC2CC2(F)F)c(F)c1

InChI Key InChIKey=YAJMPZFDYPOFQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574216   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50574216(CHEMBL4876214 | US20240000767, Example 108)
Affinity DataIC50:  0.370nMAssay Description:In Vitro Radioligand Binding Studies for Determination of the Dissociation Constants K1 at the Human Adrenoreceptor ADRA2C (Eurofins Panlabs Discover...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM50574216(CHEMBL4876214 | US20240000767, Example 108)
Affinity DataIC50:  0.370nMAssay Description:Inhibition of human alpha 2C adrenergic receptor expressed in CHO-K1 cells coexpressing Gaq and aequorin assessed as suppression of noradrenaline-ind...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed