BDBM50578390 CHEMBL4867286

SMILES COc1ccc(Cc2nc3c(-c4ccc(=O)n(C)c4)c(nc(N)n3n2)-c2ccccc2)nc1

InChI Key InChIKey=KTEXNEUQDJNGIW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578390   

TargetAdenosine receptor A2a(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50578390(CHEMBL4867286)
Affinity DataIC50: 7.70nMAssay Description:Antagonist activity at human A2aR expressed in CHO-K1 cells assessed as inhibition of cAMP accumulation preincubated for 30 mins followed by adenosin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Therachem Research Medilab

Curated by ChEMBL
LigandPNGBDBM50578390(CHEMBL4867286)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human A2bR expressed in CHO-K1 cells assessed as inhibition of cAMP accumulation preincubated for 30 mins followed by adenosin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed