BDBM50581916 CHEMBL5079043

SMILES CCCCNc1nc(N)nc2ccc(Cc3ccc(CN4CC5(COC5)C4)cc3)nc12

InChI Key InChIKey=MJIGXQDERFISLK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50581916   

TargetToll-like receptor 8(Human)
Beijing Advanced Innovation Center For Human Brain Protection

Curated by ChEMBL
LigandPNGBDBM50581916(CHEMBL5079043)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human TLR8 expressed in HEK293 cells incubated for 6 to 16 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetToll-like receptor 7(Human)
Beijing Advanced Innovation Center For Human Brain Protection

Curated by ChEMBL
LigandPNGBDBM50581916(CHEMBL5079043)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 to 16 hrs by SEAP reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed