BDBM50586817 CHEMBL5091642

SMILES CCCC[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccc(F)cc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=UKUQNPULUQDCMS-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50586817   

TargetDelta-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataIC50: 8.10nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi:  1.10E+4nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [3H]-Nisoxetine from human NET expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586817(CHEMBL5091642)
Affinity DataKi: <5.00E+4nMAssay Description:Displacement of [3H]-WIN35428 from human DAT expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed