BDBM50586822 CHEMBL5077561

SMILES CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1cc(C)c(O)c(C)c1)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SZGFKMMELMVQQF-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50586822   

TargetDelta-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataIC50: 7.80nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataIC50: 78nMAssay Description:Displacement of [3H]-DAMGO from rat mu opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataIC50: 123nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in mouse HN9.10 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]-citalopram from human SERT expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi:  1.40E+3nMAssay Description:Displacement of [3H]-Nisoxetine from human NET expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
University of The Punjab

Curated by ChEMBL
LigandPNGBDBM50586822(CHEMBL5077561)
Affinity DataKi: <5.00E+4nMAssay Description:Displacement of [3H]-WIN35428 from human DAT expressed in HEK cell membrane assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed