BDBM50587242 CHEMBL5078538

SMILES Nc1ccc(cn1)-c1cccc(c1)C(=O)N[C@H]1CN[C@H](C1)C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=RNUMWVIZGKULGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587242   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50587242(CHEMBL5078538)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of wild type Bcr-Abl (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Human)
Xi'An Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50587242(CHEMBL5078538)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of wild type Bcr-Abl T315I mutant (unknown origin) incubated for 1 hr in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed