BDBM50587838 CHEMBL5182178

SMILES [H][C@]12CN(Cc3ccc(OC)nc3)C[C@]1([H])n1nnc(c1CO2)-c1ccccc1F

InChI Key InChIKey=DFXPKDVTVWXDDK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50587838   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50587838(CHEMBL5182178)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]-(+)-pentazocine from human sigma1 receptor transfected in HEK293 cell membranes assessed as inhibition constant measured after 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
Esteve Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50587838(CHEMBL5182178)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-1,3-di-O-tolylguanidine from human sigma 2 receptor/TMEM97 transfected in sigma 1 receptor knockout HEK293 cell membranes assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed