BDBM50591251 CHEMBL5206829
SMILES CN(C(=O)[C@@H]1C[C@H](O)CN1c1nc(C)cc(c1C#N)C(F)(F)F)c1cccc(C)c1
InChI Key InChIKey=FAQDVYGMYVIYHD-YJBOKZPZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50591251
Affinity DataIC50: 24nMAssay Description:Inhibition of recombinant human full length DNA polymerase theta using DNA substrate measured after 1 hrs in presence of dNTPs by plate reader assayMore data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) assessed as end point Kd using DNA as substrate preincubated...More data for this Ligand-Target Pair
Affinity DataKd: 8.20nMAssay Description:Displacement of tracer from recombinant Tb-labeled DNA polymerase theta (unknown origin) using DNA as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair