BDBM50593956 CHEMBL5173987

SMILES CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)cc1NC1CCOCC1

InChI Key InChIKey=SARPTDQIBWRNNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593956   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593956(CHEMBL5173987)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593956(CHEMBL5173987)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed