BDBM50593964 CHEMBL5170760

SMILES Cl.Ic1ccc2NC(=O)\C(=C3/Nc4ccccc4/C/3=N\OCC(=O)N3CCNCC3)c2c1

InChI Key InChIKey=IDHNHRXOFNBMQL-WCFRLSLOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593964   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593964(CHEMBL5170760)
Affinity DataIC50:  0.450nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593964(CHEMBL5170760)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed