BDBM50593977 CHEMBL5195070

SMILES Cl.CN1CCN(CC1)C(=O)CO\N=C1\C(\Nc2ccccc\12)=C1\C(=O)Nc2ccc(Cl)cc12

InChI Key InChIKey=AZBYYJBVFCNCFE-XUAPAYBYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50593977   

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593977(CHEMBL5195070)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human recombinant His-tagged FLT3/D835Y mutant expressed in baculovirus expression system incubated for 30 mins in presence of ATP by H...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50593977(CHEMBL5195070)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant His-tagged FLT3 kinase domain (564 to 958 residues) expressed in baculovirus expression system incubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed