BDBM50595502 CHEMBL5179396

SMILES COc1ccc(-c2cn3ccc(cc3n2)N2CCNCC2)c(OCc2ccccc2)c1

InChI Key InChIKey=ABSIADNCEKEGEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50595502   

TargetToll-like receptor 9(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50595502(CHEMBL5179396)
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human TLR9 expressed in HEK-blue hTLR9 cells assessed as inhibition of CpGB-induced NFkappaB activation preincubated with comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50595502(CHEMBL5179396)
Affinity DataIC50: 1.13E+3nMAssay Description:Antagonist activity at human TLR7 expressed in HEK-blue hTLR7 cells assessed as inhibition of CL264-induced NFkappaB activation preincubated with com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed