BDBM50595705 CHEMBL5192334

SMILES CN(C(=O)c1ccnn1Cc1ccc2cc(C)c(N)nc2c1)c1ncccc1F

InChI Key InChIKey=ATPDSTVJCBICCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50595705   

TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50595705(CHEMBL5192334)
Affinity DataIC50:  14nMAssay Description:Inhibition of PRMT5 methyltransferase activity in human MTAP -/- Calu-6 cells assessed as reduction in SmB SDMA levels measured after 2 days by HTRF ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed