BDBM50597165 CHEMBL5190962

SMILES Cc1cc(cc(C)n1)-c1n[nH]cc1-c1ccc(cc1)-c1cccc(c1)S(N)(=O)=O

InChI Key InChIKey=WGWMFTZBMNPELG-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50597165   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597165(CHEMBL5190962)
Affinity DataIC50:  70nMAssay Description:Inhibition of full-length wild type LRRK2 (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADAPTA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Mus musculus)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597165(CHEMBL5190962)
Affinity DataEC50:  920nMAssay Description:Inhibition of mouse full-length LRRK2 G2019S mutant transfected in HEK293 cells using LRRKtide as substrate in presence of ATP by incubated for 1 hr ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50597165(CHEMBL5190962)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of full-length LRRK2 G2019S mutant (unknown origin) using LRRKtide as substrate incubated for 1 hr in presence of ATP by TR-FRET based ADA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed