BDBM50610920 CHEMBL5269554

SMILES Oc1cc(Cl)c(Cl)cc1NCC(=O)N1CCN(CC1)C1CN(C1)C(=O)C=C

InChI Key InChIKey=UJXQGAAQXCOWJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50610920   

TargetGTPase KRas(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50610920(CHEMBL5269554)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells incubated for 6 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed