BDBM50611437 CHEMBL5266998

SMILES CCN(Cc1cc(C)n(C[C@@H]2C[C@H]2C#N)c(=O)c1)c1ccc(F)cc1

InChI Key InChIKey=DGIGAYPQXQSHGW-IRXDYDNUSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50611437   

TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataEC50:  150nMAssay Description:Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataIC50:  1.60E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor 2(Homo sapiens (Human))TBA
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]-HBT1 from His-tagged GluA2-AMPA receptor LBD (unknown origin) in presence of glutamate by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))TBA
LigandPNGBDBM50611437(CHEMBL5266998)
Affinity DataEC50:  2.60E+4nMAssay Description:Positive allosteric modulator activity at GluN2A NMDA receptor (unknown origin) expressed in CHO cells co-expressing GluN1a in the presence of L-glut...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed