BDBM50615662 CHEMBL5279266

SMILES COc1nc2ccc(cc2c(Cl)c1Cc1ccc(cc1)C(F)(F)F)[C@@](O)(c1cnnn1C)c1ccc(C)nc1C

InChI Key InChIKey=HVSWHSCHDKSPHW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50615662   

TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615662(CHEMBL5279266)
Affinity DataIC50: 8nMAssay Description:Inhibition of human RORgammmat LBD expressed in Escherichia coli by FRET co-activator peptide assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615662(CHEMBL5279266)
Affinity DataIC50: 9nMAssay Description:Inhibition of human RORgammmat LBD expressed in HEK293T by one-hybrid reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Cadila Healthcare

Curated by ChEMBL
LigandPNGBDBM50615662(CHEMBL5279266)
Affinity DataIC50: 30nMAssay Description:Inhibition of human RORgammmat LBD expressed in HEK293T by two-hybrid reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed