BDBM50615856 CHEMBL5290716

SMILES CCn1nnc(n1)-c1sc(nc1O)-c1ccccc1O

InChI Key InChIKey=FMWAGGMQECABRZ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50615856   

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dompe Farmaceutici

Curated by ChEMBL

LigandBDBM50615856(CHEMBL5290716)Copy SMILESCopy InChI

Affinity DataIC50: 14nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in cold stimulated Ca2+ efflux preincubated for 5 mins followed by cold sti...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL

TargetTransient receptor potential cation channel subfamily M member 8(Human)
Dompe Farmaceutici

Curated by ChEMBL

LigandBDBM50615856(CHEMBL5290716)Copy SMILESCopy InChI

Affinity DataIC50: 24nMAssay Description:Inhibition of human TRPM8 expressed in HEK293 cells assessed as reduction in ethyl 4-methoxy-2-phenylthiazole-5-carboxylate induced Ca2+ efflux prein...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/23/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL