BDBM50616626 CHEMBL5422085

SMILES CC(C)(Oc1cccc(c1)C1CCCN(C1)S(=O)(=O)c1cccc(c1)-c1ccc2ccsc2c1)C(O)=O

InChI Key InChIKey=VKXUTHDVMPXIAN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50616626   

TargetB-cell CLL/lymphoma 9 protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50616626(CHEMBL5422085)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of N-terminal His6-tagged full-length recombinant beta-catenin (1 to 781 residues) (unknown origin) expressed in Escherichia coli BL21 DE3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetB-cell CLL/lymphoma 9 protein(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50616626(CHEMBL5422085)
Affinity DataIC50: 3.58E+3nMAssay Description:Inhibition of beta-catenin/BCL9 protein-protein interaction in Wnt-dependent human HCT-116 cells assessed as reduction in Axin2 expression level by q...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed