BDBM50624055 CHEMBL5400218

SMILES CC(C)c1onc(c1CN1CCN(CC1)c1cc2cc(ccc2n1C)C(O)=O)-c1c(Cl)cccc1Cl

InChI Key InChIKey=YNQWIOGVIJQVHC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624055   

TargetBile acid receptor(Human)
Hepagene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624055(CHEMBL5400218)
Affinity DataEC50:  67nMAssay Description:Agonist activity at GST-tagged human FXR-LBD in presence of luorescein-SRC2-2 coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Hepagene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624055(CHEMBL5400218)
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at human GAL4-FXR-LBD expressed in HEK293T cells assessed as transcriptional activity measured after 16 to 20 hrs by luciferase repo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed