BDBM50624064 CHEMBL5433843

SMILES COc1cc(cc2sc(nc12)N1CCN(Cc2c(onc2-c2c(Cl)cccc2Cl)C(C)C)CC1C)C(O)=O

InChI Key InChIKey=FDWVUFBIHGGQCA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50624064   

TargetBile acid receptor(Human)
Hepagene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624064(CHEMBL5433843)
Affinity DataEC50:  20nMAssay Description:Agonist activity at GST-tagged human FXR-LBD in presence of luorescein-SRC2-2 coactivator peptide by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBile acid receptor(Human)
Hepagene Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624064(CHEMBL5433843)
Affinity DataEC50:  59nMAssay Description:Agonist activity at human GAL4-FXR-LBD expressed in HEK293T cells assessed as transcriptional activity measured after 16 to 20 hrs by luciferase repo...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed