BDBM506359 US11045448, Cpd. No. 68::methyl ((1S,2R)-2-((S)-cyano(1-(3-(4-((1-((E)-4-(dimethylamino)but- 2-enoyl)azetidin-3-yl)sulfonyl)phenoxy)propyl)piperidin-4-yl)(3- fluorophenyl)methyl)cyclopentyl)carbamate

SMILES COC(=O)N[C@H]1CCC[C@@H]1[C@@](C#N)(C1CCN(CCCOc2ccc(cc2)S(=O)(=O)C2CN(C2)C(=O)\C=C\CN(C)C)CC1)c1cccc(F)c1

InChI Key InChIKey=BSNVIXWVMHSRLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506359   

TargetMenin(Human)
University of Michigan

US Patent
LigandPNGBDBM506359(methyl ((1S,2R)-2-((S)-cyano(1-(3-(4-((1-((E)-4-(d...)
Affinity DataIC50: 7nMAssay Description:A fluorescence polarization (FP) competitive binding assay was used to determine the binding affinities of representative menin inhibitors. A FAM lab...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent