BDBM508909 US11071730, Example 20B

SMILES CC(C)n1cnc2cc(nc(Nc3ccncc3F)c12)-c1ccc2c(c1)N([C@@H]1C[C@@H](C1)N1CCC(C)(C)C1)C(=O)C21CCN(CC1)C(=O)[C@@H]1CC[C@H](C)O1

InChI Key InChIKey=RRONVZWPVUGRIA-DSBLJKAWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508909   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM508909(US11071730, Example 20B)
Affinity DataIC50:  0.0500nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent