BDBM509094 2-{[(2R)-2-Amino-2-carboxyethyl]sulphanyl}-4-({(14R)-13-(3-aminopropyl)-14-[1-benzyl-4-(2,5-difluorophenyl)-1H-pyrrol-2-yl]-15,15-dimethyl-2,7,12-trioxo-10-thia-3,6,13-triazahexadec-1-yl}amino)-4-oxobutanoic acid/trifluoroacetic acid (1:2)::US11071788, Example M6

SMILES CC(C)(C)[C@@H](N(CCCN)C(=O)CSCCC(=O)NCCNC(=O)CNC(=O)CC(SCC[C@H](N)C(O)=O)C(O)=O)c1cc(cn1Cc1ccccc1)-c1cc(F)ccc1F

InChI Key InChIKey=QTYVRIKRDLVPQW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 509094   

TargetKinesin-like protein KIF11(Human)
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US Patent
LigandPNGBDBM509094(US11071788, Example M6 | 2-{[(2R)-2-Amino-2-carbox...)
Affinity DataIC50: 1.78nMAssay Description:The motor domain of the human kinesin spindle protein KSP/Eg5 (tebu-bio/Cytoskeleton Inc, No. 027EG01-XL) was incubated in a concentration of 10 nM w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent